Gain Critical Insights For Better Decision Making
With the ability to deliver comprehensive particle counting, identification, and characterization on as little as 5 µL of sample, the Aura family of instruments give gene therapy developers and manufacturers critical information while preserving precious samples early in development.
Innovative Technology Enables Early Candidate Characterization and Selection
Unlike flow imaging, which requires milliliters of sample, Aura systems can quickly and easily characterize viral vector and other types of gene therapies with just 5µL of sample. This is due to analyzing samples via membrane microscopy which requires meniscal amounts while maintaining 100% sampling efficiency.
Begin candidate screening and selection much earlier in development providing the confidence needed when commercializing your gene therapy.
Labeled DNA leakage from compromised AAV capsids (left)
Determine Root Cause of Viral Vector Instability
Leveraging Fluorescence Membrane Microscopy (FMM), interrogate your drug products to determine what’s causing aggregation and instability.
It’s widely known and accepted that DNA leakage from full but comprised AAV capsids promote aggregation. At ultra-low volumes, Aura GT enables comprehensive product characterization without wasting costly precious samples.
Featured Products
Aura+
With the ability to support the full range of development and manufacturing applications across therapeutic approaches—including protein/antibody therapeutics, gene therapies, cell therapies, and small molecules— Aura+ packs powerful flexibility into a single particle analyzer.
Features
- 5 µL to 10 mL volume
- Particle characterization for protein, cell and gene therapeutics
- Three fluorescent channels for particle identification
- 4x and 20x magnification imaging
Aura GT
Optimized for gene therapy applications, Aura GT maximizes what you can learn about your particles while minimizing the amount of sample you need to analyze.
Features
- Ultra low volume requirement - 5 µL
- Specialized in viral vector stability analysis
- Fluorescence enabled for protein and nucleic acid analysis
- Gene therapy specific assays and workflows
